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What EGFR/HER2 Vaccine Targets [Video]

Categories
Cancer Research

What EGFR/HER2 Vaccine Targets

EGFR (Epidermal Growth Factor Receptor) and HER2 (Human Epidermal Growth Factor 2) are proteins often found in over-abundance on the surface of cancer cells caused by undesired mutation.

This means that on the surface of tumor cells, roughly 10x to 100x more of these proteins are found compared to normal healthy cells.

This over-abundance causes cells to divide uncontrollably and helps the formation of new blood vessels needed for cancer to spread and invade other tissues.

EGFR/HER2 over-expression is associated with very aggressive tumor growth and poor prognosis for most cancer types.

And this is what the vaccine helps the immune system target.

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