The role of mutations in primary tumor formation and evolution [Video]

Explore the critical role of mutations in cancer development and evolution with this comprehensive lecture. Dr. Sara Ammond provides a detailed overview of how normal cells transform into cancer cells through DNA mutations, explaining the types of mutations and their impact on cell behavior.

Learn about:

Different types of mutations: substitutions, indels (insertions and deletions), amplifications, and translocations.
The significance of mutations in oncogenes and tumor suppressor genes.
Hereditary vs. somatic mutations and their implications.
The two-hit hypothesis and the accumulation of mutations leading to cancer.
Tumor heterogeneity and clonal evolution, affecting cancer treatment strategies.
Gain insights into the genetic changes that drive cancer progression and understand why mutations are central to the development and treatment of cancers. Join us as we delve into the molecular mechanisms behind cancer evolution and the complexities of targeting mutated cells in cancer therapy.