Breast Cancer Breakthroughs Episode 9: New Frontiers in Early ER-positive Breast Cancer [Video]

Some people with early estrogen receptor-positive breast cancer will experience a recurrence, but we can’t yet identify who those people are. Patients need options so they can feel confident that they’ve done everything in their power to prevent recurrence and put breast cancer behind them. In this episode of Breast Cancer Breakthroughs, you’ll learn about the newest treatments on the way for people with early ER-positive breast cancer from experts Dr. Sara Tolaney and Dr. Aditya Bardia. You’ll also hear from breast cancer survivor Tracy Cushing, who explains why patients with early breast cancer need progress and the importance of discussing your treatment goals with your doctor.
Kelsey Hampton, PhD, is Senior Manager, Mission Communications at Susan G. Komen
Tracy Cushing, M.D. is an emergency medicine physician and breast cancer survivor.
Dr. Sara Tolaney is a medical oncologist at Dana Farber Cancer Institute
Dr. Aditya Bardia is a medical oncologist at UCLA

Sign up for reminders about future episodes of Breast Cancer Breakthroughs here: https://www.komen.org/about-komen/our-impact/breast-cancer/breast-cancer-breakthroughs-series/
Link to Survey: https://susangkomen.iad1.qualtrics.com/jfe/form/SV_0iiMgwLc2FghCse
Clinical Trial Finder: https://www.breastcancertrials.org/BCTIncludes/index.html

Videos:
Under the Microscope: CDK4/6 inhibitors: Closing the express lane in breast cancer: https://youtu.be/RVy_XfOIvxk
Under the Microscope: Breast cancer stages: https://youtu.be/F0t2FcaSXwU
Under the Microscope: Tumor profiling tests: Tools to predict risk of recurrence: https://youtu.be/xvL6sPiqA-g
Under the Microscope: Breast cancer recurrence: When cancer comes back: https://youtu.be/JBKwKOpNsxs
Under the Microscope: Estrogen receptor: Unlocking breast cancer cell division: https://youtu.be/h8cLqjly1xM
Breast Cancer Breakthroughs: Bringing Treatments to Life: https://youtube.com/live/7ZSXKkGW2Cw?feature=share
Breast Cancer Breakthroughs: Navigating Breast Cancer Recurrence: https://youtube.com/live/j2Ym9GEnHo4?feature=share

Resources:
Breast cancer stages and staging: https://www.komen.org/breast-cancer/diagnosis/stages-staging/
Breast Cancer Recurrence: https://www.komen.org/breast-cancer/treatment/recurrence/
Emerging Areas in Drug Therapies for Early Breast Cancer: https://www.komen.org/breast-cancer/treatment/emerging-areas/drug-therapies/
Hormone Therapies: https://www.komen.org/breast-cancer/treatment/type/hormone-therapy/
CDK4/6 Inhibitors: https://www.komen.org/breast-cancer/treatment/type/cdk4-6-inhibitors/
Immunotherapy: https://www.komen.org/breast-cancer/treatment/type/immunotherapy/
Oncotype DX test: https://www.komen.org/breast-cancer/diagnosis/factors-that-affect-prognosis/oncotype-dx/

Clinical Trials Mentioned in Episode:
monarchE trial (Active, not recruiting): https://classic.clinicaltrials.gov/ct2/show/NCT03155997
NATALEE trial (Active, not recruiting): https://clinicaltrials.gov/study/NCT03701334

00:00 Introduction
01:45 New options for early ER-positive breast cancer
10:18 NATALEE Trial
13:36 Weighing risks and benefits of treatments
15:33 Optimizing new treatments for patients
18:34 Conclusion