Advanced HCC: Treatment options for patients ineligible for IO – patient case video

Explore treatment options, adverse event management and next steps in this patient case video on advanced hepatocellular carcinoma (HCC) and treatment options for patients ineligible for IO presented by Prof. Sammy Saab.

Go to the interactive version of this patient case video where you can interact and engage with valuable information, challenging questions, and clickable resources. You’ll choose your preferred 1st line treatment option for a patient who is not eligible for IO, explore how to manage adverse events, and work through the next step after progression on 1st line treatment: https://cor2ed.com/

Clinical Takeaways

– There is a cohort of patients with advanced HCC who are not eligible for immunotherapy as 1st line treatment option

– This cohort consists of post-transplant recurrent patients or patients who have underlying active or uncontrolled auto-immune disease

– Tyrosine Kinase Inhibitors (TKIs), such as sorafenib and lenvatinib, would be the preferred 1st line treatment options for these patients

– Adverse events (AE) management for TKIs can either be dose interruption, reduction or discontinuation, depending on the type and severity of the AE