A New Breakthrough in Rectal Cancer Treatment: Dostarlimab [Video]

The future of rectal cancer treatment might be here! Dostarlimab is rewriting the rules by potentially eliminating the need for gruelling chemo, radiation, and surgery for some patients. This video dives deep into how dostarlimab harnesses the body’s immune system to fight cancer, specifically focusing on its effectiveness for patients with mismatch repair-deficient (MMR-deficient) locally advanced rectal cancer. Traditionally, these tumors have poor treatment options, but dostarlimab is showing incredible promise in shrinking or even eliminating them altogether. Early trials boast a 100% response rate for patients with this specific mutation, potentially eliminating the need for further invasive procedures. However, dostarlimab is still under investigation, and more research is needed.

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⏰Timecodes⏰
0:00 Intro
0:23 Standard Treatment
1:15 The Hypothesis
2:18 The Study Design and Patients
3:49 Main Results and Side Effects
4:46 Endoscopy
5:24 Viable Cancer Cells
5:49 Final Remarks
6:53 Outro

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📖References📖
Clinical Trial.gov – https://clinicaltrials.gov/study/NCT04165772

🔬Paper Referenced 🔬
Cercek et al. – https://www.nejm.org/doi/full/10.1056/NEJMoa2201445

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About: Cancer with Leah is focused on looking at cancer holistically. This channel focuses on educational content and answers questions related to cancer and examines scientific studies.

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